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Explore how α-ketoglutarate, a central TCA cycle intermediate, emerges as a powerful longevity compound through epigenetic regulation, hormetic stress responses, and caloric restriction mimicry. Discover its mechanisms from molecular to organismal levels.
Discover the intricate molecular mechanisms behind resveratrol's anti-aging effects, from sirtuin activation to AMPK pathways. Explore how this remarkable compound triggers cascades of cellular protection, mitochondrial enhancement, and longevity pathways.
Discover how metformin—originally derived from French lilac—accidentally became one of the most powerful anti-aging drugs ever studied. Learn the fascinating molecular mechanisms that make this humble diabetes medication a cellular fountain of youth.
Discover how exercise combats aging at the cellular level through AMPK activation, mitochondrial biogenesis, senescent cell clearance, and longevity pathway optimization. Learn the molecular science behind exercise's anti-aging effects.
Metformin, well-known as an antidiabetic medication, research indicates, may also have anti-aging effects!